Face recognition is a prevailing authentication solution in numerous biometric applications. Physical adversarial attacks, as an important surrogate, can identify the weaknesses of face recognition systems and evaluate their robustness before deployed. However, most existing physical attacks are either detectable readily or ineffective against commercial recognition systems. The goal of this work is to develop a more reliable technique that can carry out an end-to-end evaluation of adversarial robustness for commercial systems. It requires that this technique can simultaneously deceive black-box recognition models and evade defensive mechanisms. To fulfill this, we design adversarial textured 3D meshes (AT3D) with an elaborate topology on a human face, which can be 3D-printed and pasted on the attacker’s face to evade the defenses. However, the mesh-based optimization regime calculates gradients in high-dimensional mesh space, and can be trapped into local optima with unsatisfactory transferability. To deviate from the mesh-based space, we propose to perturb the low-dimensional coefficient space based on 3D Morphable Model, which significantly improves black-box transferability meanwhile enjoying faster search efficiency and better visual quality. Extensive experiments in digital and physical scenarios show that our method effectively explores the security vulnerabilities of multiple popular commercial services, including three recognition APIs, four anti-spoofing APIs, two prevailing mobile phones and two automated access control systems.