Auxiliary-free human video matting methods, which rely solely on input frames, often struggle with complex or ambiguous backgrounds. To tackle this, we propose MatAnyone, a practical framework designed for target-assigned video matting. Specifically, building on a memory-based framework, we introduce a consistent memory propagation module via region-adaptive memory fusion, which adaptively combines memory from the previous frame. This ensures stable semantic consistency in core regions while maintaining fine details along object boundaries. For robust training, we present a larger, high-quality, and diverse dataset for video matting. Additionally, we incorporate a novel training strategy that efficiently leverages large-scale segmentation data, further improving matting stability. With this new network design, dataset, and training strategy, MatAnyone delivers robust, accurate video matting in diverse real-world scenarios, outperforming existing methods. The code and model will be publicly available.